11/25/20

Postdoc position

Within the context of the Bill & Melinda Gates Foundation-funded project “Transformative strategy for controlling rice disease in developing countries” the research group of Prof. Dr. Wolf B. Frommer at Heinrich Heine Universität, Düsseldorf, Germany, is offering a Post Doc position in

Advanced breeding technologies (all gender)

Project: Developing blight resistant rice lines using advanced breeding methods

Rice is the world’s most important staple food and is mainly cultivated by small scale producers in low and middle-income countries. Bacterial leaf blight caused by the bacteria Xanthomonas oryzae pv. oryzae (Xoo), is a major problem in the cultivation of rice and can result in significant yield losses. The “Healthy Crops” team aims to achieve food security for smallholder farmers in Africa and Asia by providing resistant rice varieties that can be introduced in local elite lines. The specific project aims are to develop resistant lines using transgene-free genome editing, for example through the use of nanoparticles, in combination with novel methods that facilitate regeneration of plants from protoplasts. The project also involves CRISPR protein guide RNA complex purification. Experience in cell culture and protoplast regeneration is advantageous, extensive experience in molecular biology and biochemistry is important.

For further information click here

If you are interested, please send your application including a CV, names and email addresses of three references, and a one-page motivation letter as a single pdf document to Prof. Dr. Wolf B. Frommer (apply_Postdoc_BMGF(at)hhu.de).


11/25/20

Postdoc position

Within the context of the Bill & Melinda Gates Foundation-funded project “Transformative strategy for controlling rice disease in developing countries” the research group of Prof. Dr. Wolf B. Frommer at Heinrich Heine Universität, Düsseldorf, Germany, is offering a Post Doc position in

Rice Blast Resistance (all gender)

Project: Developing rice lines resistant to the blast causing fungus Magnaporte grisea

Rice is the world’s most important staple food and is mainly cultivated by small scale producers in low and middle-income countries. Rice blast, caused by the plant-pathogenic fungus M. grisea, causes is one of the most serious diseases affecting rice. Our international team aims to develop rice lines that are resistant to M. grisea. The specific project aims at determining the role of nutrition for virulence, for example by exploring whether and how nutrient efflux transporters are hijacked by the pathogen to secure key resources necessary for efficient reproduction. Candidate host genes will be identified, and mutants will be analyzed for resistance

For further information click here

If you are interested, please send your application including a CV, names and email addresses of three references, and a one-page motivation letter as a single pdf document to Prof. Dr. Wolf B. Frommer (apply_Postdoc_BMGF(at)hhu.de).


11/20/20

Master Thesis

Genome sequencing of rice varieties and evaluation of the efficiency of CRISPR-mediated genome editing

Tools: Nextgen Sequencing und Bionformatics

Genome editing provides an elegant new research tools that enables the targeted alteration of specific regions in plant genomes. The goal of the project will be to determine the sequence of rice varieties as well as genome-edited lines and to identify possible off target effects, somaclonal events and the efficacy of removal of the T-DNA.

DNA will be extracted from various elite lines of rice as well as edited lines, followed by Illumina sequencing at an external company. Subsequently, genome assembly will be performed and sequences will be analyzed for differences in the genomes of parental and filial lines using bioinformatics.

The thesis will be performed under supervision of Dr. Thomas Hartwig and Dr. Van Thi Luu.

Requirements:

  • Experience with Linux
  • Background in statistics

Advantageous:

  • Basic experience in molecular biology (DNA extraction)
  • Knowledge in bioinformatics
  • Advanced computer skills

Start date: As soon as possible

Send your application with CV to:

Applications_MPP(at)hhu.de

Responsible for the content: E-MailProf. Dr. Wolf B. Frommer